Protein Details: Glycine receptor subunit alpha-4

Protein ID

ICDB_Pro_1033

Protein Name

Glycine receptor subunit alpha-4

Gene Name

Glra4

Organism

Mus musculus (Mouse)

Length

456 amino acids

AlphaFoldDB

AF-Q61603-F1-model_v4.pdb

Function

Sequence

MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESRFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLLKEGETMRKLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

236-241;295

Disease

Location

Detected in the retina inner plexiform layer; especially at the border between layer three and four (at protein level).